HIGH-THROUGHPUT VIRTUAL SCREENING WITH E-PHARMACOPHORE AND MOLECULAR SIMULATIONS STUDY IN THE DESIGNING OF PANCREATIC LIPASE INHIBITORS

High-throughput virtual screening with e-pharmacophore and molecular simulations study in the designing of pancreatic lipase inhibitors

Ganesh Kumar Veeramachaneni, K Kranthi Raj, Leela Madhuri Chalasani, Jayakumar Singh Bondili, Venkateswara Rao Talluri Department of Biotechnology, K L University, Guntur, India Background: Obesity is a progressive metabolic disorder in the current world population, and is characterized by the excess deposition of fat in the adipose tissue.Pancreat

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Complete Controllability Conditions for Linear Singularly Perturbed Time-Invariant Systems with Multiple Delays via Chang-Type Transformation

The problem of complete controllability of a linear time-invariant singularly-perturbed system with multiple commensurate non-small delays in the slow state variables is considered.An approach to the time-scale separation of the original singularly-perturbed system by means of Chang-type non-degenerate transformation, fr3345 generalized for the sys

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